Alzheimer’s disease — named after German physician Alois Alzheimer, who first described the disease in 1906 — is the most common of all elderly dementias, affecting an estimated 24 million people worldwide. It’s a progressive disease of t
Is dying from Alzheimers disease or disease at age 19 or cancer or stroke or cardiovasular 20 young? Is like cancer or lung cancer, cardiovascular disease or something, dying
Alzheimers DiseaseOne area of clinical research is focused on treating the underlying disease pathology! Reduction of amyloid beta levels is a common target of compounds under investigation! Immunotherapy or vaccination for the amyloid protein is one treatment modality under study! Unlike preventative vaccination, the putative therapy would be used to treat people already diagnosed! It is based upon the concept of training the immune system to recognise, attack, and reverse deposition of amyloid, thereby altering the course of the disease! An example of such a vaccine under investigation was ACC-001, although the trials were suspended in 2008! Another similar agent is bapineuzumab, an antibody designed as identical to the naturally induced anti-amyloid antibody! Other approaches are neuroprotective agents, such as AL-108, and metal-protein interaction attenuation agents, such as PBT2! A TNFα receptor fusion protein, etanercept has also showed encouraging results! Also, in 2008, two separate clinical trials showed positive results in modifying the course of disease in mild to moderate AD with methylthioninium chloride, a drug that inhibits tau aggregation and dimebon, an antihistamine!
Alzheimer's disease n. A disease marked by the loss of cognitive ability, generally over a period of 10 to 15 years, and associated with the.
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